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Patients experiencing rash during the 14-day lead-in period of 200 mg day should not have their viramune dose increased until the rash has resolved.

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Nevirapine must be given in combination with other antiviral medications and it should not be used alone.

You should stop breast-feeding if you are taking VIRAMUNE. It is in general recommended that you do not breast-feed if you have HIV infection because it is possible that your baby can become infected with HIV through your breast milk.

If clinical hepatitis occurs.characterised by anorexia.nausea.vomiting.icterus AND laboratory findings (such as moderate or severe liver function test abnormalities (excluding GGT)).nevirapine must be permanently stopped. Viramune must not be readministered to patients who have required permanent discontinuation for clinical hepatitis due to nevirapine.

If liver problems or skin/allergic reactions occur while you are taking this medication once daily.seek immediate medical attention and do not increase the dose to twice daily.

The active substance in Viramune.nevirapine.is a non-nucleoside reverse-transcriptase inhibitor (NNRTI). It blocks the activity of reverse transcriptase.an enzyme produced by HIV-1 that allows it to infect cells in the body and make more viruses. By blocking this enzyme.Viramune.taken in combination with other antiviral medicines.reduces the amount of HIV-1 in the blood and keeps it at a low level. Viramune does not cure HIV-1 infection or AIDS.but it may delay the damage to the immune system and the development of infections and diseases associated with AIDS.

Advise the patient to read the FDA-approved patient labeling ( Medication Guide ).

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these outcomes include all subjects who were randomized after the 14 day lead-in with immediate-release viramune and received at least one dose of blinded study medication.

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