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Sildenafil is primarily used to treat erectile dysfunction or impotency.and pulmonary hypertension. Erectile dysfunction is a condition in Entocort order which there is a lack of power or strength to attain and maintain erection for sexual intercourse. This drug relaxes the muscles and improves the blood flow by inhibiting the enzyme which is responsible for the blocking of the blood vessel and widens the blood vessel to allow free flow of blood to the penis during sexual arousal. its brand Viagra contains Sildenafil citrate as the active ingredient. It gets absorbed in the body quickly after consumption and enters the bloodstream where it blocks the actions of the key enzyme phosphodiesterase type 5.also called as PDE-5. Due to this there is an instant upsurge in the concentration of nitric oxide (NO) and the enzyme guanylyl cyclase. The enzyme guanylyl cyclase then increase the biosynthesis of cyclic GMP which is a potent vasodilator and widens the blood vessels in the body as well as in the penile region. The enzyme cGMP also has another function of relaxing the penile smooth muscles. Hence.together.both these actions lead to enhancement in the blood circulation to the penis and blood to be retained for prolonged period of time so as to achieve a long lasting and firm erection. Action of Caverta lasts buy caverta online almost 4-5 hours after consumption and hence.this is helpful in indulging into long-lasting sexual activity.

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In patients receiving HIV drugs and alpha-blockers sildenafil dose adjustment is required. Such individuals should use the minimal dose of sildenafil.which is 25mg. A daily dose of alpha-blockers should be taken prior buy caverta online Caverta intake.well in advance (at least 2 hours before sildenafil).

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