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Clozaril clozapine is available only through a distribution system that ensures monitoring of white blood cell wbc count and absolute neutrophil count anc according to the schedule described below prior to delivery of the next supply of medication.

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an electrolyte imbalance (such as low levels of potassium or magnesium in your blood).

No specific pharmacokinetic studies were conducted to investigate the effects of renal or hepatic impairment on the pharmacokinetics of clozapine. Higher clozapine plasma concentrations are likely in patients with significant renal or hepatic impairment when given usual doses.

Clozapine can also cause seizures.especially in higher doses. Let your doctor or pharmacist know if you have ever had seizures. While taking this medication.avoid driving or other activities during which a sudden loss of consciousness could be dangerous (e.g..operating heavy machinery.swimming).

If you are using the liquid form of this medication.read the Patient Information Leaflet if available from your pharmacist before you start taking clozapine and each time you get a refill. If you have any questions.ask your doctor or pharmacist.

This medicine also has a black-box warning because it may cause seizures. You should tell your doctor if you have a history of seizures.head injuries.or brain tumors before Price gyne-lotrimin taking clozapine.

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