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The most frequent adverse reaction to ZYLOPRIM (allopurinol) is skin rash. Skin reactions can be severe and sometimes fatal. Therefore.treatment with ZYLOPRIM (allopurinol) should be discontinued immediately if a rash develops (see WARNINGS ). Some patients with the most severe reaction also had fever.chills.arthralgias.cholestatic jaundice.eosinophilia and mild leukocytosis or leukopenia. Among 55 patients with gout treated with ZYLO-PRIM for 3 to 34 months (average greater than 1 year) and followed prospectively.Rundles observed that 3% allopurinol price without insurance patients developed a type of drug reaction which was predominantly a pru-ritic maculopapular skin eruption.sometimes scaly or exfolia-tive. However.with current usage.skin reactions have been observed less frequently than 1%. The explanation for this decrease is not obvious. The incidence of skin rash may be increased in the presence of renal insufficiency. The frequency of skin rash among patients receiving ampicillin or amoxicillin concurrently with ZYLOPRIM (allopurinol) has been reported to be increased (see PRECAUTIONS ).

ache (flu-like symptoms). The rash may progress to widespread blistering and peeling of the.

Drink at least eight glasses of water or other fluids each day while taking allopurinol unless directed to do otherwise by your doctor.

Allopurinol is allopurinol price without insurance used to prevent or treat high uric acid levels that may be caused by cancer medicines or for patients with kidney stones that contain calcium.

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